Cyclamate
Cyclamate was a serendipitous discovery at the University of Illinois in 1937. A patent was obtained, which became property of Abbott Laboratories in North Chicago, Illinois.
After toxicological studies were completed, sodium cyclamate was given GRAS approval by the FDA in 1949. Approval of calcium cyclamate followed a few years later.
Initially, cyclamate was available only in tablet form as a product for diabetics.
Consumption was expanded greatly when cyclamate-saccharin blends became widely available as special dietary foods.
Cyclamate is the generic term for the cyclohexylsulfamates. The two commercially available salts, sodium cyclamate and calcium cyclamate, are both noncaloric, white crystalline powders.
They readily dissolve in water to form solutions stable to light, heat, and air throughout the pH range of 2 to 12.
Cyclamate is the least intense of the widely used alternative sweeteners.
Cyclamate is approximately thirty times as sweet as sugar. At high concentrations it has a significant bitter-sour off-taste.
A blend of ten parts cyclamate to one part saccharin provides a synergistic sweetening effect while masking off-taste problems inherent to both components when used separately.
Cyclamate
